14 results
Hypokalemia Differential Diagnosis Algorithm

Low intake 
• poor oral intake 

Renal loss 
• Medication 
• Hypomagnesemia 
•
Diagnosis Algorithm ... Low intake ... tubular acidosis ... • Gitelman's ... #Causes #Classification
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Diagnosis Algorithm ... Extra-renal Losses ... Bartter syndrome, Gitelman ... #causes #potassium ... #low #nephrology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Causes of Hypokalemia ... • Renal tubular ... acidosis (type ... Bartter's syndrome, Gitelman's ... #causes #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
thiazide-sensitive sodium ... thiazide-sensitive sodium ... alkalosis • Normal or low ... (renal potassium ... tubular acidosis
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Algorithm Before ... suggests extra-renal ... Bartter syndrome, Gitelman ... - Metabolic acidosis ... #low
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Urinary Chloride Algorithm ... alkalosis • Normal/low ... Bartter syndrome, Gitelman ... the indicated causes ... the excretion of sodium
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
GI Losses - Gastric
 • Vomiting
 • NG suction
GI
Causes of Metabolic ... Chloridorrhea Renal ... Losses - Impaired tubular ... Hypomagnesemia • Barrter's/Gitelman's ... #Causes
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... Villous adenoma Renal ... chewing tobacco, Renal ... tubular acidosis ... diuretic use), Gitelman's
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Intake: • Low ... - Diarrhea • RENAL ... - Bartter - Gitelman ... filtration rate by tubulo-glomerular ... metabolic acidosis
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
time you have a case ... normal volume-based algorithm ... can be high or low ... Present (Uosm ≥100): Hypovolemia ... #nephrology