7 results
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
Neurological event 2) ... Sodium loss from ... tubules 3) Naturiesis ... #Cerebral #SaltWasting ... #hyponatremia #
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Diagnosis Algorithm ... Serum Osmolarity 2) ... Urine Osmolarity 3) ... Low Uric Acid → SIADH ... #nephrology #sodium
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Repeat the sodium ... Step 2. ... administration Step 3. ... EUVOLEMIC • SIADH ... Diagnosis #Workup #Algorithm
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
time you have a case ... normal volume-based algorithm ... , Renal Sodium loss ... Present (Uosm ≥100): Hypovolemia ... #nephrology
Hyponatremia - Differential Algorithm
Isotonic Hyponatremia: Hyperlipidemia, Hyperproteinemia, Recent TURP
Hypotonic Hyponatremia: 
 • Hypovolemia: Diuretics/Nephropathies, Vomiting, Diarrhea,
Algorithm Isotonic ... : • Hypovolemia ... • Euvolemia: SIADH ... #diagnosis #causes ... #nephrology #sodium
SIADH Treatment Options
1. Treat underlying cause of SIADH: Pain, Primary lung pathology, Post-operative phenomenon, Medications, Basically
Treat underlying cause ... Basically anything 2. ... hospitalization) 3. ... promoting passive sodium ... #Management #hyponatremia
Hyponatremia Differential Diagnosis Algorithm in Cancer
UOsm ≥ 100 mOsm/kg = Urine is inappropriately concentrated for hypotonic
Hyponatremia Differential ... Diagnosis Algorithm ... appropriate • Hypovolemia ... CAR-T- and IL-2- ... inappropriate • SIAD