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management differential signs sle syndrome disease druginduced erythematosus gca systemic workup activation aion algorithm ana anteriorischemicopticneuropathy antibodies antinuclear approach arteritis
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
or nerve root Symptoms ... present both at rest ... trauma (e.g., meniscal ... Joint #Pain #MSK #rheumatology ... #differential #diagnosis
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... of Systemic Lupus ... of hip (rare), Arthritis ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... meningitis), MCC CNS symptoms ... Behcet syndrome (Clinical ... management #signs #symptoms ... #rheumatology #
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... likely it will be clinically ... Juvenile Idiopathic Arthritis ... ANA #patterns #rheumatology ... #diagnosis #differential
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... (to support a diagnosis ... ANA and RF (if clinical ... #testing #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Differential Diagnosis ... Non-autoimmune rheumatologic ... : • Symptoms limited ... #Rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Constitutional symptoms ... , Arthritis, myalgia ... comparison #table #rheumatology ... #diagnosis #management
Anterior ischemic optic neuropathy (AION) - Recognition of giant cell arteritis (GCA) 1) Is visual loss caused
of giant cell arteritis ... thrombosis of short ... Clinical manifestations ... GiantCellArteritis #GCA #Rheumatology ... Ophthalmology #Diagnosis
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Systemic lupus ... SJIA], systemic lupus ... Liver function tests ... Activation #Syndrome #Diagnosis ... #Rheumatology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... the “Chewing gum test ... them, but urgent rheumatology ... absence of visual symptoms ... Temporal #Signs #Symptoms
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