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differential rheumatology classification monoclonal ra signs agglutinin algorithm arthritis causes cold cryofibrinogenemia deficiency dehydrogenase disease elevated extraarticular ferritin gammopathy hemolytic
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... of anemia include ... Diagnosis: • hemolytic ... anemia • Cold ... #anemia #hematology
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Iron Deficiency Anemia ... extravascular) hemolysis ... athletic training, Pulmonary ... diet, Alcoholism, Tea-toast ... Algorithm #ferritin #hematology
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
- Differential Diagnosis ... Legionnaires disease • Pulmonary ... tumor burden) Vasculitis ... associated with any symptoms ... #differential #diagnosis
Clinical Classification of Pulmonary Hypertension 1. Pulmonary arterial hypertension from pulmonary vasculopathy Idiopathic pulmonary arterial hypertension Heritable gene mutations
Schistosomiasis - Chronic hemolytic ... anemia - Persistent ... multifactorial mechanisms Hematologic ... neurofibromatosis, vasculitis ... Classification #Diagnosis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... Presentation: Systemic Symptoms ... • Progressive symptoms ... infiltrates, hemoptysis ... #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... progressing GN • New pulmonary ... well as inner ear ... Presentation - Systemic Symptoms ... #rheumatology #
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
blood vessels (vasculitis ... reticularis Blood: Anemia ... infiltration damages tear ... pathophysiology #signs #symptoms ... #diagnosis #ExtraArticular
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
Summary Framework Hematologic ... No evidence of anemia ... constitutional symptoms ... insufficiency, Anemia ... #diagnosis #oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Coombs (-) hemolytic ... anemia due to cold ... Paraproteinemias #Hematology ... #Differential #Diagnosis ... #Oncology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Cryofibrinogenemia Symptoms ... malignancies, vasculitis ... thrombophlebitis, pulmonary ... Cryofibrinogenemia Diagnosis ... hematology
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