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rheumatology druginduced summary treatment classes comparison ddxof differential dil em erythematosus fever hemophagocytic hlh lymphohistiocytosis nephritis nephrology sbi seriousbacterialillness systemic
Lupus Nephritis Primer Class I - Minimal Mesangial Class II - Mesangial Proliferative Class Ill - Focal Proliferative Class IV
Lupus Nephritis ... #Nephritis #SLE ... #Classification ... #Classes #differential ... #diagnosis #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... and Management ... Positive in 60-80% of cases ... of SLE • Evolution ... Erythematosus #Diagnosis
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Discontinuation of causal ... Usual therapeutic management ... of SLE • Evolution ... #rheumatology #diagnosis ... #management
Serious Bacterial Illness (SBI): 1) UTI and pyelonephritis Most common cause of SBI Accounts for 3-8% of uncharacterized fevers Female
pyelonephritis Most common cause ... Consider BCx, CSF evaluation ... presentation Urinalysis: LE ... unformed) PNA diagnosed ... #Peds #EM #Classification
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
+ Etiological Assessment ... for etiological assessment ... Autoimmune diseases: SLE ... inhibitors under evaluation ... #management #treatment
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
is rare in DIL, SCLE-DIL ... Discontinuation of causal ... cutaneous-DIL • Evolution ... #rheumatology #diagnosis ... #treatment #management
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