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diagnosis liver management differential injury aclf aih autoimmune causes chemistry cirrhosis dili druginduced gastroenterology hematology hyperlipidemia interpretation lfts mds myelodysplasia
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... Infections Alcohol-Associated ... Hepatitis (AAH) ... #Hepatology #gastroenterology
Alcoholic Hepatitis - Management Algorithm 1. Severity assessed not only by MDF (>32) but also by MELD
Alcoholic Hepatitis ... - Management Algorithm ... only increase short-term ... #Algorithm #treatment ... #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... non-essential drug/HDS treatments ... HEV, EBV, CMV), Alcohol-related ... dechallenge • Acute ... #hepatology
Alcoholic Hepatitis - Management Algorithm Assess Eligibility for Treatment: - Maddrey Discriminant Function ≥ (or possibly MELD
Alcoholic Hepatitis ... - Management Algorithm ... : - Acute kidney ... - Multiorgan failure ... #Algorithm #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Liver Failure ( ... ALT Ratios: • Alcoholic ... > 2 • NASH, Chronic ... injury: > 3 • Chronic ... #differential #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... ALT Ratios: • Alcoholic ... > 2 • NASH, Chronic ... injury: > 3 • Chronic ... #hepatology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
subclinical disease to acute ... liver failure ... - Symptoms of chronic ... regarding need for treatment ... Diagnosis #Management #Hepatology
Secondary Causes of Hyperlipidemia Nunerous secondary causes of hyperlipidemia exist; screening for the presence of these underlying
Diabetes mellitus, Chronic ... renal failure, ... Stress, Sepsis, Alcohol ... Glucocorticoid treatment ... hepatitis, Systemic
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Pinpoint-sized red spots ... • Bone Marrow Failure ... • Chronic Myelogenous ... arsenic compounds, alcohol ... Syndromes #diagnosis #hematology
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