8 results
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Alcohol-Associated Hepatitis ... Liver Injury (DILI ... ) Viral Hepatitis ... #Acute #Chronic
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
non-essential drug/HDS treatments ... dechallenge • Acute ... hepatitis fibrosis ... • Autoimmune hepatitis ... #hepatology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
Autoimmune Hepatitis ... - Symptoms of chronic ... pattern of liver injury ... Other Etiology of Hepatitis ... #Autoimmune #Hepatitis
Alcoholic Hepatitis - Management Algorithm
1. Severity assessed not only by MDF (>32) but also by MELD
Alcoholic Hepatitis ... only increase short-term ... survival in severe AH ... #Alcoholic #Hepatitis ... #treatment #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... Autoimmune: Autoimmune hepatitis ... viral hepatitis ... #hepatitis #differential ... #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
viral hepatitis ... viral hepatitis ... Liver Failure (ALF ... viral hepatitis ... #differential #Hepatology
Alcoholic Hepatitis - Management Algorithm
Assess Eligibility for Treatment:
 - Maddrey Discriminant Function ≥ (or possibly MELD
Alcoholic Hepatitis ... - Management Algorithm ... injury with serum ... #Alcoholic #Hepatitis ... #hepatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: • Acute ... erythematosus (ACLE ... Noninfectious hepatitis ... Hematologic: • AIHA ... with Lupus: • Chronic