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diagnosis oncology ana antibodies bcnie behcet bloodculture clinical disease endocarditis gammopathy gap globulin infectiousdiseases infective management mds mgus myelodysplasia myelodysplastic
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Significance (MGUS) - Differential ... Diagnosis Neurologic-Centered ... capillary leak syndrome ... • Schnitzler syndrome ... #Diagnosis #hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Can Feature A Monoclonal ... et diutinum Neurologic ... Amyloidosis and monoclonal ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... microscopy and serial ... SLE), Sjogren's Syndrome ... ANA #patterns #rheumatology ... #diagnosis #differential
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
skin injury) • Neurologic ... Medium and large ... Behcet disease) Differential ... refractory disease : monoclonal ... signs #symptoms #rheumatology
Blood Culture-Negative Infective Endocarditis (BCNIE) Definition: No etiology found after 3 separate blood cultures remain negative for
requires special media ... factors: - Serology ... - Assays for antinuclear ... antiphospholipid syndrome ... Endocarditis #diagnosis #differential
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Exposure to heavy metal ... Workup: • Complete ... blood count with differential ... #diagnosis #hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... primary condition MEDIUM ... affects the skin, neurologic ... cognitive impairment, neurologic ... #Diagnosis #Rheumatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... changes (POEMS syndrome ... gastric tumors • Hematology ... Gap #ProteinGap #differential ... #diagnosis #hematology
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