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diagnosis causes hematology cardiology oncology pericarditis algorithm aplastic edema erythematosus extravascular facial hemolysis hemolytic intravascular management monoclonal palpitations paraproteinemias physicalexam
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Dyskeratosis congenita • Drugs ... - Cytotoxic drugs ... - Antithyroid medications ... - Hepatitis, eosinophilic ... #oncology #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
) - HELLP syndrome ... usually IgG) (e.g. lupus ... infection) - Drugs ... Extravascular #Causes #differential ... #anemia
Causes of Pericarditis - Differential Diagnosis Algorithm Viral: • Coxsackie • Echovirus • Adenovirus • Epstein-Barr virus
Pericarditis - Differential ... arthritis • Systemic lupus ... Post-cardiac injury syndrome ... Metabolic: • Uremia ... Myxedema Other: • Medication
Facial Swelling - Differential Diagnosis Framework for Facial Edema Infectious: • Dental abscess • Ludwig's angina • Vincent's angina • Cellulitis •
Facial Swelling - Differential ... angioedema with eosinophilia ... Preeclampsia Dermatologic ... edema of acne Medications ... anti-inflammatory drugs
Causes of Acute Pericarditis: Infectious; Viral: Adenovirus Coxsackie virus A and B Echovirus Epstein-Barr virus Hepatitis Human immunodeficiency
- related Medication ... induced (select drugs ... pericarditis) Uremia ... Systemic lupus ... #Pericarditis #Differential
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 Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
(-) hemolytic anemia ... to cold IgG • Lupus ... Episodic angioedema+eosinophilia ... Paraproteinemias #Hematology ... #Monoclonal #Differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... lymphopenia, low PLT • Anemia ... extremities Drug ... • Antihistone: Drug ... activation and/or medications
Palpitations - Differential Diagnosis Framework What? • It is an unpleasant awareness or sensation that the heart is
Palpitations - Differential ... PALPITATIONS: Medications ... • Serotonergic drugs ... Hyperthyroidism • Anemia ... #Differential #
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