10 results
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
duration), Several medications ... /HDS treatments ... for alternative causes ... dechallenge • Acute ... #Algorithm #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... , Recreational Drugs ... #Diagnosis #Causes ... #Acute #algorithm ... #hepatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... cases, drug-dependent ... Discontinuation of causal ... Lupusreference #druginduced ... #diagnosis #management
Angioedema - Classification Diagnosis and Treatment
Types of Angioedema:
 • Acute allergic angioedema - Usually occurs with
Diagnosis and Treatment ... Angioedema: • Acute ... • Non-allergic drug ... first taking the medication ... #Treatment #management
Drug Induced Systemic Lupus Erythematosus
> 100 drugs have been associated with drug-induced SLE
High risk (>5%):
 •
for 1 year of treatment ... Lupusreference #DrugInduced ... Erythematosus #medications ... #risk #differential ... #diagnosis #rheumatology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Edema in 70% of cases ... Resolution > 15 days Differentials ... • SJS/TEN • Acute ... disease: symptomatic treatment ... #diagnosis #management
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... : • Acute cutaneous ... permanent alopecia Differential ... extremities Drug ... activation and/or medications
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Drug Induced Lupus ... cases, drug-dependent ... #Lupus #DIL #rheumatology ... #diagnosis #treatment ... #management
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... circulation If drugs ... - HIV/HAART medications ... #Diagnosis #causes ... #typea #typeb #classification
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Reversible course Differential ... Electrolyte abnormality, Medication ... /Drug toxicity, ... • Treatment of ... #management #neurology