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hematology oncology anemia aplastic causes chronic gap inherited lymphocytic management mds myelodysplasia myelodysplastic platelet protein proteingap syndromes table workup
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Diagnosis: • ... Cytopenias: • Neutropenia ... , anemia, thrombocytopenia ... increase in gamma globulins ... #oncology #hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Diagnosis Algorithm ... Leukemia, Tumour ... ITP • SLE • CLL ... Diagnosis #Algorithm ... #Causes #Hematology
Inherited Qualitative Platelet Defects Bernard-Soulier Syndrome • Defect of adhesion due to a lack of GP Ib/IX/V
Bernard-Soulier Syndrome ... structure and cell ... #comparison #table ... #differential # ... diagnosis #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
- Antithyroid medications ... virus (EBV) • Leukemia ... antithymocyte globulin ... Anemia #oncology #hematology ... #diagnosis #management
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
leukemia • Solitary ... changes (POEMS syndrome ... gastric tumors • Hematology ... Gap #ProteinGap #differential ... #diagnosis #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Chronic Myelogenous Leukemia ... Cell Leukemia ... Myeloproliferative Disease • Neutropenia ... blood count with differential ... #diagnosis #hematology
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