12 results
DOAC Cheat Sheet
 • Apixaban, Dabigatran, Edoxaban, Rivaroxaban
 • Renal Dosing
 • Common Drug interactions
 •
Apixaban, Dabigatran, Edoxaban ... , Rivaroxaban • ... Renal Dosing • ... anticoagulation #CheatSheet #dosing ... #ckd #pharmacology
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
anticoagulant dosing ... Dabigatran #Apixaban #Rivaroxaban ... #Edoxaban #Loading ... #DVT #Pharmacology ... #Hematology
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
if CrCl < 50) Edoxaban ... Anticoagulation #Hematology ... #Pharmacology # ... Apixaban #Rivaroxaban ... #Dabigatran #Edoxaban
Switching Between Anticoagulants and DOACs
VKA, Dabigatran, Rivaroxaban, Apixaban, Edoxaban, Betrixaban, DOAC, Parenteral anticoagulant

DOI: 10.1161/JAHA.120.017559

#Anticoagulants #DOACs #anticoagulation
VKA, Dabigatran, Rivaroxaban ... , Apixaban, Edoxaban ... anticoagulation #Switching #hematology ... #pharmacology
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Betrixaban (Bevyxxa), Edoxaban ... (Lixiana), Rivaroxaban ... anticoagulation #doac #noac #pharmacology ... #hematology #reversal
Xa Inhibitors - Apixaban and Rivaroxaban 
Oral Xa inhibitors are recommended by CHEST as first-line for
- Apixaban and Rivaroxaban ... indications and edoxaban ... overview of the dosing ... for apixaban and rivaroxaban ... #Dosing #Pharmacology
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
Currently, edoxaban ... and rivaroxaban ... being stronger for edoxaban ... for appropriate dosing ... Anticoagulation #Management #Hematology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
Edoxaban, rivaroxaban ... Rivaroxaban and ... pathway whereas edoxaban ... Chemotherapy #Oncology #Hematology ... Interactions #Table #Pharmacology
Warfarin to DOAC and DOAC to Warfarin Transitions 

Here are a couple of charts to help
DOACs for easier dosing ... Rivaroxaban is < ... Edoxaban is <2.5 ... Anticoagulation #Pharmacology
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
During the initiation ... diagnosis #models #hematology ... inhibitor #Apixaban #Rivaroxaban ... #Edoxaban #heparin