9 results
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
correlations • Purpura ... (5%): PAN > GPA ... hemopathies (4%) • Cryoglobulinemia ... #dermpath #dermatology ... #clinical #manifestations
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... GPA causes disease ... • Mixed cryoglobulinemia ... #dermatology #rash ... #diagnosis #rheumatology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Cryoglobulinemia ... Syndrome: • Clinical ... • Vasculitis ... classification #rheumatology ... #vasculitis
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
the Skin - Differential ... purpura, Hemorrhagic ... Urticarial/LCV) - Cryoglobulinemic ... #skin #dermatology ... #rheumatology #
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
PURPURA: Vasculitis ... /HSP • Cryoglobulinemia ... Diagnosis #hematology ... #rheumatology # ... #dermatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
skin lesions ... ANCA +MPO) • Cryoglobulinemic ... Vasculitis - Skin ... Low levels mixed cryoglobulinemia ... #rheumatology #
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... skin lesions • ... / ANCA + MPO) Cryoglobulinemic ... Skin lesions (red ... #Rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
, small-vessel vasculitis ... panuveitis, retinal vasculitis ... , palpable purpura ... MCC-small vessel vasculitis ... #rheumatology #
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
malignancies, vasculitis ... , sepsis or cryoglobulinemia ... Calciphylaxis • Cryoglobulinemia ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology