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diagnosis rheumatology classification cutaneous symptoms behcet cryofibrinogenemia cryoglobulinemia cryoglobulins dermatologic dermpath gca giantcell granulomatosis lesions manifestations pathology polyangiitis rash semiology
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
the Skin - Differential ... nodules, Deep ulcers ... : • Behcet Disease ... • Cogan syndrome ... #skin #dermatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... • Goodpasture syndrome ... • Giant cell arteritis ... #dermatology #rash
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
(Clinical Dx). ... ) Differential Diagnosis ... Lymphoma Ocular melanoma ... #diagnosis #management ... #signs #symptoms
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
Identification of causes ... Connective tissue disease ... (5%): PAN > GPA ... #dermpath #dermatology ... #semiology #signs
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... genital aphthous ulcers ... purpura: strong sign ... • ANCA (Dx: GPA ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Differential Diagnosis ... purpura: Strong sign ... tract, and often causes ... #Rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Purpura - Skin ulcers ... : • Clinical triad ... • Autoimmune diseases ... - GPA, EGPA, microscopic
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
arteritis (GCA) ... Diagnosis = clinical ... systemic sx + signs ... very remarkable w/differential ... #Diagnosis #Management
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
malignancies, vasculitis ... sensitivity • Painful ulcers ... to medium-sized arteries ... Antiphospholipid syndrome ... #hematology
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