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Common Etiologies of Cirrhosis

Inflammation

 - Hepatitis B (15 percent)

 - Hepatitis C (47 percent)

 - Schistosomiasis
Inflammation - Hepatitis ... 15 percent) - Hepatitis ... Nonalcoholic fatty liver ... 14 percent) #Diagnosis ... #Differential #Hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
- Differential Diagnosis ... • NAFLD • Cirrhosis ... Chronic Viral Hepatitis ... • Acute Viral Hepatitis ... #hepatology #transaminitis
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
those with CLD (± cirrhosis ... (DILI) Viral Hepatitis ... #Failure #Cirrhosis ... #Hepatology #gastroenterology ... #management #diagnosis
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... CMV), Alcoholic cirrhosis ... #Patterns #Liver ... #Injury #hepatology ... #differential #diagnosis
Hepatomegaly - Differential Diagnosis Algorithm
Malignant
 • Primary Carcinoma
 • Metastases
 • Lymphoma
 • Leukemia
 • Polycythemia
- Differential Diagnosis ... Non-Malignant • Fatty Liver ... Primary Biliary Cirrhosis ... #Differential #Diagnosis ... Algorithm #Causes #Hepatology
Signs of Chronic Liver Disease ( Cirrhosis )

#Diagnosis #Cirrhosis #Signs #Symptoms #Hepatology
Signs of Chronic Liver ... Disease ( Cirrhosis ... ) #Diagnosis ... #Cirrhosis #Signs ... #Symptoms #Hepatology
Ascites - Differential Diagnosis
Chronic liver disease (cirrhosis or chronic hepatitis) - 80%
Underlying malignancy - 10%
Congestive heart
- Differential Diagnosis ... Chronic liver disease ... (cirrhosis or chronic ... hepatitis) - 80% ... #hepatology
Cirrhosis leading to Chronic Liver Failure - Clinical Signs and Symptoms

#Cirrhosis #LiverFailure #Signs #Symptoms #PhysicalExam #Findings
Cirrhosis leading ... to Chronic Liver ... and Symptoms #Cirrhosis ... PhysicalExam #Findings #Diagnosis ... #Hepatology
Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
of Severe Acute Liver ... Injury - Ichemic hepatitis ... - Drug-Induced liver ... #Differential #Hepatology ... #Diagnosis
 End Stage Liver Disease (Cirrhosis) - Complications 
 • Ascites
 • Esophageal Varices
 • Hepatic
End Stage Liver ... Disease (Cirrhosis ... #Cirrhosis #Complications ... #diagnosis #management ... #summary #hepatology