6 results
 Acute Iron Poisoning

There are five classically described phases of toxicity:
Gastrointestinal phase (~6 hours post-ingestion)
 -
caustic mucosal injury ... multi-organ failure (ARDS ... caustic bowel injury ... Poisoning #Toxicity #Toxicology ... #Diagnosis #Management
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Presentation: Injury ... extensors of the arms ... Diagnosis: • ... #diagnosis #management
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Acidosis (MALA) Pathophysiology ... anaerobic metabolism Diagnosis ... and acute kidney injury ... LacticAcidosis #Toxicity #Toxicology ... #Diagnosis #Management
In ARDS, we know that the lungs are so diffusely injured that the remaining total area
In ARDS, we know ... are so diffusely injured ... , lung injury may ... #pathophysiology ... #diagnosis #management
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Difficulty raising the arms ... Direct muscle injury ... Risk of muscle injury ... Atorvastatin Diagnosis ... #management #treatment
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
cytotoxic lung injury ... organizing pneumonia, ARDS ... pneumonitis Diagnosis ... suggestive but not diagnostic ... #management #Toxicology