10 results
Cyanide Toxicity 
Treatment:
1) Hydroxocobalamin + Cyanide = Cyanocobalamin (nontoxic) 
   or 
2) Amyl nitrite
Cyanide Toxicity ... #Cyanide #Toxicity ... #Toxicology #Pathophysiology ... #Management #Treatment
 Acute Iron Poisoning

There are five classically described phases of toxicity:
Gastrointestinal phase (~6 hours post-ingestion)
 -
caustic mucosal injury ... multi-organ failure (ARDS ... caustic bowel injury ... #Toxicology #Diagnosis ... #Management #Ferrous
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Acidosis (MALA) Pathophysiology ... and acute kidney injury ... LacticAcidosis #Toxicity ... #Toxicology #Diagnosis ... #Management
Salicylate Toxicity - Diagnosis and Management

Clinical Findings
Pathophysiology
Workup
Treatment

By Stacy Marshall, MD

#Salicylate #Toxicity #Diagnosis #Management #Toxicology #Aspirin #Treatment
Salicylate Toxicity ... Diagnosis and Management ... Clinical Findings Pathophysiology ... #Salicylate #Toxicity ... #Toxicology #Aspirin
Noncardiogenic Pulmonary Edema - Differential Diagnosis Framework

NCPE Pathophysiology:
Noncardiogenic pulmonary edema occurs because of excessive pulmonary capillary
Framework NCPE Pathophysiology ... distress syndrome (ARDS ... • Salicylate toxicity ... contents • Head injury ... Traumatic brain injury
In ARDS, we know that the lungs are so diffusely injured that the remaining total area
In ARDS, we know ... are so diffusely injured ... , lung injury may ... #pathophysiology ... #diagnosis #management
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Induced Muscle Toxicity ... Direct muscle injury ... Risk of muscle injury ... Statin #muscle #toxicity ... myopathy #diagnosis #management
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
Amiodarone Induced Lung Toxicity ... cytotoxic lung injury ... organizing pneumonia, ARDS ... Pulmonary #diagnosis #management ... #Toxicology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Etiology: • Pathophysiology ... Medication/Drug toxicity ... Seizures: Treat with AEDs ... Syndrome #diagnosis #management
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Presentation: Injury ... extensors of the arms ... Myelitis #diagnosis #management