9 results
Euglycemic Diabetic Ketoacidosis (EuDKA)
SGLT2 Inhibitors
Increasing Indications
Significant Adverse Drug Effects
Definition of EuDKA
 • Metabolic acidosis with pH
Ketoacidosis (EuDKA ... Definition of EuDKA ... level < 200 mg/dL Pathophysiology ... #diagnosis #management ... #endocrinology
 Acute Iron Poisoning

There are five classically described phases of toxicity:
Gastrointestinal phase (~6 hours post-ingestion)
 -
caustic mucosal injury ... multi-organ failure (ARDS ... caustic bowel injury ... #Toxicology #Diagnosis ... #Management #Ferrous
Noncardiogenic Pulmonary Edema - Differential Diagnosis Framework

NCPE Pathophysiology:
Noncardiogenic pulmonary edema occurs because of excessive pulmonary capillary
- Differential Diagnosis ... Framework NCPE Pathophysiology ... distress syndrome (ARDS ... • Salicylate toxicity ... #differential #diagnosis
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Acidosis (MALA) Pathophysiology ... and acute kidney injury ... LacticAcidosis #Toxicity ... #Toxicology #Diagnosis ... #Management
In ARDS, we know that the lungs are so diffusely injured that the remaining total area
In ARDS, we know ... are so diffusely injured ... , lung injury may ... #pathophysiology ... #diagnosis #management
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Induced Muscle Toxicity ... Direct muscle injury ... Risk of muscle injury ... #myopathy #diagnosis ... #management #treatment
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
cytotoxic lung injury ... organizing pneumonia, ARDS ... pneumonitis Diagnosis ... #Pulmonary #diagnosis ... #management #Toxicology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Etiology: • Pathophysiology ... factor PRES Diagnosis ... Medication/Drug toxicity ... Seizures: Treat with AEDs ... #management #neurology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Presentation: Injury ... extensors of the arms ... bouts of HTN Diagnostic ... #management #neurology