10 results
Primary Adrenal Insufficiency:
 • ACTH stimulation test - Synthetic ACTH does not stimulate cortisol secretion because
ACTH stimulation test ... aldosterone - Low in cases ... in which injury ... autoantibody tests ... diagnosis #testing #endocrinology
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
enzyme 21-OHase causes ... 21-OHD in the adrenal ... #21HydroxylaseDeficiency #21OHD ... #pathophysiology ... #genetics #endocrinology
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Diagnosis and Management ... syndrome, Electrical injury ... Dermatomyositis) AKI - Pathophysiology ... extracellular fluid into injured ... #Summary #causes
Adrenal Insufficiency - Diagnosis and Management Summary
Primary Adrenal Insufficiency:
Most Common Cause in the US: Autoimmune Adrenalitis
Other
Diagnosis and Management ... A STIM test can ... ACTH STIM TEST: ... Secondary #Diagnosis #Management ... #Endocrinology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
malignancy Pathophysiology ... glucose suppression test ... or refractory cases ... #Endocrinology ... #Treatment #Pathophysiology
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
injury), Coags ... anti-GBM) Other tests ... Goodpasture's cause ... hematuria, RBC casts ... differential #diagnosis #management
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Diagnosis and Management ... Weakness, cramping, nausea ... , rhabdo/crush injury ... Cortisol+ACTH stim test ... only if no clear cause
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Presentation: Injury ... negative, MOG-IgG test ... • Infectious causes ... Myelitis #diagnosis #management
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
indirect Coombs test ... , DIC, hypoTN, renal ... Causes purpura & ... Related Acute Lung Injury ... Transfusions #diagnosis #management
Scleroderma Renal Crisis (SRC)

Clinical Presentation of Scleroderma Renal Crisis:
1) Acute kidney injury
2) Abrupt onset of hypertension
3)
) Acute kidney injury ... anemia (MAHA) Pathophysiology ... endothelial cell injury ... of arteries Management ... • Refractory cases