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diagnosis product reactions alcoholic algorithm anemia aplastic childhood classification hemophagocytic hepatitis hepatology hlh hodgkins immunization lymphohistiocytosis lymphoma pediatrics peds rheumatology
Childhood Immunization Schedule: Why we immunize • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
metabolites induce injury ... CNS and hematologic ... disseminates in blood ... fetal blood vessel ... peds #pediatrics #pathophysiology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Phagocytosis of blood ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Marrow (Toxic injury ... and petechiae Causes ... result from low blood ... #hematology #diagnosis ... #management
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... Related Acute Lung Injury ... Infection - Infection ... Transfusion #diagnosis #management ... #hematology #reactions
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Causes purpura & ... Related Acute Lung Injury ... • Infection - ... Transfusions #diagnosis #management ... #hematology #reactions
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... Workup: • Full Blood ... marrow biopsy - if blood ... classification #hematology ... #oncology #management
Alcoholic Hepatitis - Management Algorithm Assess Eligibility for Treatment: - Maddrey Discriminant Function ≥ (or possibly MELD
exclude other causes ... - Screen for infection ... with chest x-ray, blood ... - Acute kidney injury ... #Algorithm #hepatology
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