14 results
Myositis Specific Antibodies (MSAs)

Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE
Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ
Immune Mediated
Antibodies (MSAs ... , TIF1y, NXP2, Mi ... Anti-Synthetase Syndrome ... #Specific #Antibodies ... clinical #diagnosis #rheumatology
Idiopathic Inflammatory Myopathies - 
Dermatomyositis (DM), Immune-Mediated Necrotizing Myopathy (IMNM), Antisynthetase Syndrome (ASS), Inclusion Body Myositis
Antisynthetase Syndrome ... Inclusion Body Myositis ... Idiopathic #Myopathy #Comparison ... Managment #algorithm #Rheumatology ... #Differential
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... others (RNP, aPL antibodies ... LAC) • Sjogren Syndrome ... Peptide (CCP) • Myositis ... , Others: SRP, Mi
Dyspnea - Differential Diagnosis Framework

Cardiovascular Causes of Dyspnea:
 • Myocardium:
	- Heart failure
	- CAD/ACS
	- Valvulopathy
 • Electrical:
	-
Dyspnea - Differential ... Hepatopulmonary syndrome ... - Transverse myelitis ... • Hematology: ... #dyspnea #sob #differential
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Weakness - Differential ... disorder (Cardiac, pulmonary ... • Acute stroke syndromes ... EMG) studies • MRI ... #Weakness #Differential
Inflammatory Myopathies
Dermatomyositis
 • Onset: Subacute
 • Pattern: Proximal
 • CK: Up to 50X ULN
 • Autoantibodies:
Anti-MDA5, anti-Mi ... Inclusion Body Myositis ... Inflammatory #Myopathies #differential ... #diagnosis #comparison ... #rheumatology #
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
SLE), Sjogren's Syndrome ... , Myositis, Mixed ... , Interstitial Pulmonary ... ANA #patterns #rheumatology ... #diagnosis #differential
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
PSS: Sjogren syndrome ... CTILD #Diagnosis #Differential ... #Comparison #Table ... #Pulmonary #Rheumatology
Features That Differentiate Acute Pericarditis from Myocardial Ischemia or Infarction and Pulmonary Embolism

In contrast to the
Features That Differentiate ... Infarction and Pulmonary ... associated with rheumatologic ... pain, such as MI ... #Presentation #comparison
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitides - Differential ... Conjunctivitis, mucositis ... • Cogan Syndrome ... C-ANCA) pattern: antibodies ... #diagnosis #rheumatology