11 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
plateletcount), peripheral blood ... smear, HIV/HCV testing ... K), H. pylori test ... thyroid function test ... #Workup #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
indirect Coombs test ... Crossmatch - involves testing ... false negatives on testing ... Transfusions #diagnosis #management ... #hematology #reactions
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... Out Secondary Causes ... Myeloproliferative Disease ... Treatment: Goals: Treating ... Syndromes #diagnosis #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
hallmark for the disease ... value is low, tests ... of Peripheral blood ... and decreased platelet ... indirect antiglobulin tests
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... TRALI): Leading cause ... false negatives on testing ... Transfusion #diagnosis #management ... #hematology #reactions
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
Qualitative defect in platelets ... characteristic of a platelet ... cascade is intact - test ... discern these causes ... fibrinogen levels, and testing
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
ABO incompatible blood ... • Severe Liver Disease ... Treat primary cause ... #treatment #management ... #hematology
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
of liver disease ... Caused by intrapulmonary ... IPVDs Diagnostic Testing ... passage • Arterial blood ... 10 minutes of rest
Pheochromocytoma - Diagnosis and Management Summary
10 percent rule = 10% of pheochromocytomas are extra-adrenal, multiple, bilateral,
Diagnosis and Management ... malignant, pediatric cases ... palpitations, tremor ... resistance, impaired fasting ... Treatment • Operable disease
Chagas Disease - American Trypanosomiasis - Diagnosis and Management Summary
Chagas disease (American trypanosomiasis) is an infectious
Diagnosis and Management ... caused by the protozoan ... Blood (platelets ... Confirmatory Tests ... and immunoblot (TESA