11 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
smear, HIV/HCV testing ... PT, aPTT(liver disease ... K), H. pylori test ... thyroid function test ... #Workup #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
indirect Coombs test ... Crossmatch - involves testing ... false negatives on testing ... Transfusions #diagnosis #management ... #hematology #reactions
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
an underlying cause ... Better call hematology ... As with many disease ... Best to have an ... Algorithm #workup #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
hallmark for the disease ... value is low, tests ... Fibrin degradation products ... indirect antiglobulin tests ... Diagnosis #Workup #Hematology
D-dimer
Plasma D-dimer is a product of clot breakdown, released upon degradation of polymerized, crosslinked fibrin. Elevated
Plasma D-dimer is a product ... age, which can cause ... false positive tests ... adjusted d-dimer testing ... pathophysiology #hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... TRALI): Leading cause ... false negatives on testing ... Transfusion #diagnosis #management ... #hematology #reactions
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
of liver disease ... Caused by intrapulmonary ... IPVDs Diagnostic Testing ... 10 minutes of rest ... #treatment #hepatology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
initial screening test ... elevated, HFE gene testing ... of liver disease ... algorithm #diagnosis #management ... #hepatology #gastroenterology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
highly inflammatory disease ... Liver function tests ... Fibrin degradation products ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
cascade is intact - test ... discern these causes ... liver function tests ... fibrinogen levels, and testing ... Differential #Diagnosis #Hematology