34 results
Carpal Tunnel Syndrome: Pathogenesis and clinical findings
 • Dysthesias - Tingling, burning, or painful sensation at
Pathogenesis and clinical ... Thenar muscle wasting ... Hypalgesia - Diminished sensitivity ... CarpalTunnel #Syndrome #pathophysiology
Ohle R et al. Clinical Examination for Acute Aortic Dissection: A Systematic Review and Meta-analysis. AEM
Clinical Examination ... Dissection #Aorta #Testing ... Signs #Accuracy #Sensitivity
Abdominojugular (Hepatojugular) Reflux

Described by Pasteur in 1885 as a physical sign of TR. Still useful for
with reasonable sensitivity ... Resource limited setting ... #PhysicalExam #Clinical
Traditionally, we have been taught to examine for Kernig’s and Brudzinski’s signs when examining patients with
JAMA rational clinical ... evidence and low sensitivity ... they do recommend testing
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... especially in the setting ... likelihood of negative clinical ... Bandemia had a sensitivity ... CBC #hematology #pathophysiology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
should be based on clinical ... • JC-virus PCR sensitivity ... analysis has a sensitivity ... of serum CrAg testing ... comparable to CSF testing
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives
1,3-Beta-D-Glucan
 • Cell wall component of many fungi
Galactomannan Testing ... Sensitivity Specificity ... cut-offs defined in clinical ... >90% (In most clinical ... Galactomannan #Fungal #Testing
Lewy Body Dementia: Pathogenesis and Clinical Findings
Lewy Body Dementia is a sub-category of major or mild
Pathogenesis and Clinical ... Clinical manifestations ... • Neuroleptic sensitivity ... LewyBody #Dementia #pathophysiology
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
dermatidis • Sensitivity ... cut-offs defined in clinical ... : Mucorales • Sensitivity ... disease - Sensitivity ... Frozen ice-pops (in setting
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski)

Brudzinski's sign is characterized
While the pathophysiology ... meningitis, it has low sensitivity ... Sign #Meningitis #Clinical