7 results
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Pathophysiology ... H+ secretion → Hypokalemia ... Metabolic alkalosis ... #Pathophysiology ... #nephrology #diagnosis
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Hypokalemia Evaluation ... Pressure: - Metabolic ... Alkalosis: Emesis ... Hippurate - Metabolic ... differential #potassium #nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Hypovolemia, UNa > 20: 
 • Renal losses, Diuretic excess,
Diagnosis Algorithm Hypovolemia ... tubal acidosis and metabolic ... alkalosis, Ketonuria ... Hypovolemia, UNa ... Algorithm #Causes #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
hypomagnesemia • Metabolic ... alkalosis • Normal ... Hypochloremic metabolic ... #diagnosis #nephrology ... #management #pathophysiology
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
alkalosis ↓ ↑ ... alkalosis/Resp ... D-lactate (short bowel syndrome ... MDaniyalHashmi1 #AcidBase ... Diagnosis #Summary #Nephrology
Gitelman Syndrome - Diagnosis and Workup
Blood Work:
 - Hypokalemia
 - Hypomagnesemia
 - Metabolic Alkalosis
 - Elevated
Gitelman Syndrome ... Blood Work: - Hypokalemia ... Hypomagnesemia - Metabolic ... Alkalosis - Elevated ... Diagnosis #Workup #nephrology
Bulimia Nervosa: Complications
GASTROINTESTINAL
 • Dehydration & inability to digest food -> Constipation
 • Recurrent vomiting exposes
• Boerhaave syndrome ... alkalosis (loss ... abuse may lead to metabolic ... ) • Overall: hypokalemia ... Complications #pathophysiology