Causes of Hyponatremia - Differential Diagnosis Algorithm Hypovolemia, UNa > 20: • Renal losses, Diuretic excess, Mineral corticoid deficiency, Salt-losing deficiency, Bicarbonaturia with renal tubal acidosis and metabolic alkalosis, Ketonuria, Osmotic diuresis, Cerebral salt wasting syndrome Hypovolemia, UNa < 20: • Extrarenal losses, Vomiting, Diarrhea, Third spacing of fluids, Burns, Pancreatitis, Trauma Euvolemia, UNa > 20: • Glucocorticoid deficiency, Hypothyroidism, Stress, Drugs, Syndrome of inappropriate antidiuretic hormone secretion Hypervolemia, UNa > 20: • Acute or chronic renal failure Hypervolemia, UNa < 20 • Nephrotic syndrome, Cirrhosis, Cardiac failure #Hyponatremia #Differential #Diagnosis #Algorithm #Causes #nephrology
