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NINDS Diagnostic Criteria for Guillain Barre Syndrome 
Features Required for Guillain-Barré Syndrome:
 • Progressive muscle weakness
symptoms or signs, Cranial ... nerve involvement ... encephalitis spectrum disorders ... #Syndrome #diagnosis ... #criteria #neurology
Localizing Extraocular Movement Disorders
 • CN Ill (Oculomotor) Nerve Palsy 
 • CN IV (Trochlear) Nerve
palsy • Medial ... One-and-a-half Syndrome ... Skew Deviation Casey ... ophthalmology #neurology ... #differential #diagnosis
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Diagnosis: • ... #Syndrome #diagnosis ... #management #treatment ... #neurology
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... Tumor • Motor Nerves ... Poliomyelitis, Guillain-Barre ... #differential #diagnosis ... #neurology
Upper Extremity Dermatomes and Myotomes
Motor Function
Shoulder:
 • Abduction - C5,C6 (axillary)
 • Adduction - C6, C7,
hand" ± Horner Syndrome ... nerve in the radial ... Carpal Tunnel Syndrome ... Dermatomes #Myotomes #diagnosis ... #neurology #sensory
Causes of Hemiplegia - Differential Diagnosis Algorithm
Cerebral Hemisphere (Contralateral motor cortex)
 • Aphasia
 • Apraxia
 •
Causes of Hemiplegia ... Sub-Cortical (Corona radiata ... Nerve Palsies ... Brown-Sequard Syndrome ... #Hemiplegia #Neurology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... Incidence: 1 to 2 cases ... all extremity, facial ... #Syndrome #diagnosis ... #management #neurology
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Causes of Fatigue ... Tuberculosis • Epstein-Barr ... Pulmonary Disease Neurologic ... • Somatization Disorder ... Chronic Fatigue Syndrome
Hearing Loss - Differential Diagnosis Framework

Hearing Loss Types:
• Conductive
• Sensorineural
• Mixed
Presbycusis is the most common type
- Differential Diagnosis ... include a: • Neurologic ... II ○ Susac’s syndrome ... Mitochondrial disorders ... Labyrinthitis ○ Epstein-Barr
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
and Differential Diagnosis ... heart failure, neurologic ... with electrolyte disorders ... Neurologic disorders ... , and Guillain-Barre