39 results
Candidates for Medical Treatment of Ectopic Pregnancy with Methotrexate 
 - Hemodynamically stable 
 - No
Pregnancy with Methotrexate ... examination #Methotrexate
High Dose Methotrexate - Toxicities and Pharmacology

Ashley & Brooke Barlow PharmD @theABofPharmaC

#High #Dose #Methotrexate #Pharmacology #oncology
High Dose Methotrexate ... #High #Dose #Methotrexate
Methotrexate Renal Toxicity 
Prevention:
 • Alkalinize the urine, keep urine ph >7
 • Start pre-treatment 12
Methotrexate Renal ... until levels of methotrexate ... @kdjhaveri #Methotrexate
Managing patients taking DMARDs #Management #Screening #PrimaryCare #Rheum #DMARDs #DMARD #BMJ #Methotrexate #Leflunomide #Sulphasalazine #Hydroxychloroquine #Monitoring
DMARDs #DMARD #BMJ #Methotrexate
Methotrexate Toxicology 

Intravenous leucovorin (folinic acid) treatment serves as a cofactor necessary for synthesis of thymidylate
Methotrexate Toxicology ... Kat_Watson #Methotrexate
Treatment Schema for Standard-Risk Acute Lymphoblastic Leukemia
Induction: 
 • Vincristine, Steroid (dexamethasone), L-Asparaginase, Intrathecal (IT) methotrexate
Consolidation
Intrathecal (IT) methotrexate ... protection: • IT methotrexate ... mercaptopurine, Weekly oral methotrexate ... pneumonia, IT methotrexate ... L-Asparaginase, IT methotrexate
Rheumatoid Arthritis - ACR 2021 Guidelines
 - Low Disease Activity
 - Moderate to High Disease Activity
Disease Activity - Methotrexate
JAK Inhibitors in 2019

Role in the therapeutic strategy in 2019
 • RA: 2nd line after failure
• Superior to methotrexate ... combination of methotrexate
Cancer agents and Electrolyte Disorders
 • Hypocalcemia: Cisplatin from Low Mg, Cetuximab- due to low Mg
Axitinib,
hypophysitis, Methotrexate ... inhibitors- fanconi, Methotrexate
Folate Deficiency - Causes of Decreased Folic Acid
↓ Intake: Diet, Age, Alcohol
↑ Demand: Pregnancy, Infancy, Hemolysis,
resection Drugs: Methotrexate