20 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
kg/day vs. 2.5 mg ... Dexamethasone 10 mg ... q12h -> 10 mg q6h ... #management #hematology ... #oncology
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Clonus, Babinski’s sign ... • Lhermitte’s sign ... patients with clinically ... stimulation Clinical ... #management #neurology
Chagas Disease - American Trypanosomiasis - Diagnosis and Management Summary
Chagas disease (American trypanosomiasis) is an infectious
Trypanosomiasis - Diagnosis ... and Management ... Romana's sign ... Indeterminate form (No signs ... #Management #Treatment
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
knees, shoulders Signs ... • Ultrasound Diagnosis ... : CLINICAL DIAGNOSIS ... Rheumatoid #Arthritis #diagnosis ... #management #rheumatology
Anterior ischemic optic neuropathy (AION) - Recognition of giant cell arteritis (GCA)

1) Is visual loss caused
Clinical manifestations ... Doppler US : halo sign ... GiantCellArteritis #GCA #Rheumatology ... Ophthalmology #Diagnosis
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
Related Disease Clinical ... PET-CT Imaging (→ Diagnostic ... Glucocorticoids (0.6 mg ... #management #phenotypes ... workup #treatment #rheumatology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
minimal tumor burden Diagnosis ... immunophenotype Clinical ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Etoposide/VP16 (100 mg ... #management #treatment ... #summary #rheumatology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
chest (in a V-sign ... shoulders (in a shawl sign ... Inverse Gottron’s sign ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... systemic sx + signs ... per day or 1 mg ... them, but urgent rheumatology ... #Management