31 results
diagnosis differential management hepatology anemia liver rheumatology algorithm causes laboratory lfts reactions thrombocytopenia transfusion treatment workup coagulation disease interpretation oncology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Bilirubin: RBC (hemolysis ... LDH: Heart, RBC (hemolysis ... intestines, White blood ... Gilbert's syndrome • Hemolysis ... #differential #Hepatology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
= (Retic %) x (Hct ... long (in days) it ... Retroperitoneal, Uterine • Hemolysis ... Microangiopathic hemolytic ... Production #Index #hematology
Hemostasis Physiology The blood's response to blood vessel injury can be viewed as four interrelated steps. Roman
blood's response to blood ... ADP, adenosine diphosphate ... #Hemostasis #Pathophysiology ... Coagulation #Cascade #Hematology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Gilbert's syndrome • Hemolysis ... Bilirubin: RBC (hemolysis ... LDH: Heart, RBC (hemolysis ... intestines, white blood ... diagnosis #algorithm #hepatology
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
to 280 U/L • It ... deficiency of red blood ... ischemic hepatitis (ALT-to-LDH ... viral hepatitis (ALT-to-LDH ... The presence of macro-LDH
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Diagnosis: • hemolytic ... Immunoglobulin M (IgM) • Blood ... Mycoplasma, EBV, HIV ... sensitize red blood ... #anemia #hematology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
phosphate: Impairs Vit ... deficiency • blood ... collection with EDTA Pathophysiology ... pressure - Elevated Vit ... Hyophosphatasia #hepatology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook Presentation: • Plts ↓50% (nadir
Thrombocytopenia (HIT ... ♀, ↑Age, ESRD Pathophysiology ... false ⊕’s, so use Bayesian ... Management: • D/c all ... Management #Treatment #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
plateletcount), peripheral blood ... smear, HIV/HCV ... not required in all ... or if a primary hematologic ... Causes #Workup #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion ... • Febrile Non-Hemolytic ... May have drop in Hct ... Extremely rare - HIV ... diagnosis #management #hematology
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