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Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
, verrucous) - Lung ... Hypercoagulable (APLAS) Microbiology ... Cerebral > Splenic, Pulmonary ... Cholesterol emboli syndrome ... hematuria, + RF Treatment
Lung Abscess
Microbiology:
 • Polymicrobial 
 • Anaerobes (most common) 
Clinical: 
 • Indolent symptoms that evolve
Lung Abscess Microbiology ... , hemoptysis Treatment ... meropenem) #Lung ... Abscess #Diagnosis #Pulmonary
Hantavirus
Pathogen: Hantavirus - Rodents are the primary reservoir
Transmission:
 • Shed in the urine, feces, saliva of
Cardiopulmonary Syndrome ... • Autopsy PCR Treatment ... diagnosis #management #treatment ... #microbiology # ... infectiousdiseases
Cystic Lung Disease
Upper Lobe Predominant: 
Langerhans Cell Histiocytosis, Pneumocystis Jiroveci, Hypersensitivity Pneumonitis, Neurofibromatosis Type 1, Paracoccidioidomycosis,
Cystic Lung Disease ... Ehlers-danlos Syndrome ... nickmmark #Cystic #Lung ... differential #diagnosis #causes ... #pulmonary
Hypoxemic Respiratory Failure - Differential Diagnosis Framework
DECREASED INSPIRED OXYGEN
 • Low PATM Can decrease first part
obesity-hypoventilation syndrome ... : Interstitial lung ... ventilation (V) in the lungs ... bypassing the lungs ... hepatopulmonary syndrome
ILD of Known Cause - Differential Diagnosis
Exposure:
 • Occupational: Asbestosis, Silicosis, Hypersensitivity, Pneumonitis
 • Treatment Related:
ILD of Known Cause ... Pneumonitis • Treatment ... BrighamChiefs #ILD #Causes ... #interstitial #lung ... #disease #pulmonary
Interstitial Lung Diseases (ILD)
Exposure-Related ILD (a.k.a. extrinsic allergic alveolitis): 
 • Hypersensitivity pneumonitis, Farmer's lung, Bird
ILD caused by inhalation ... • Idiopathic pulmonary ... Churg Strauss syndrome ... #differential #pulmonary ... #causes
Causes of Hypoxemia- Differential Diagnosis Algorithm
Ventilation/perfusion Mismatch
 • Airway Disease (Asthma, COPD)
 • Vascular (PE*)
 •
Causes of Hypoxemia ... • Interstitial lung ... Hypoventilation Syndrome ... Diagnosis #Algorithm #Causes ... #Pulmonary
Causes of Pleural Effusion - Differential Diagnosis Algorithm
Transudate - Hydrostatic
 • Congestive heart failure
 • Constrictive
Causes of Pleural ... Pneumonectomy • Trapped lung ... Malignancy • Pulmonary ... Pleural #Effusion #Pulmonary ... Algorithm #Hepatology #causes
Hemoptysis - Differential Diagnosis Framework
Airways: 
 • Bronchitis
 • Bronchiectasis
 • Malignancy: Primary bronchogenic CA, Endobronchial
westermani, PNA, Lung ... Pneumonitis, GPA, Behcet syndrome ... , Idiopathic pulmonary ... Osler-Weber-Rendu syndrome ... #causes