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diagnosis algorithm anemia differential hematology management classification cobalamin deficiency dequervains elevatedmcv endocrinology icucard macrocytic macrocytosis nutrition subacute thyroid thyroiditis vitamin
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Microcytic ( ... Infections Macrocytic ... Folate deficiency, B12 ... Orotic aciduria, Drugs ... (e.g., hydroxyurea
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Corpuscular Volume (MCV ... Blood Smear • Drugs ... Increased Requirement (e.g ... Liver Disease #Macrocytic
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Corpuscular Volume (MCV ... Chronic Disease (e.g ... (>100 fL) • B12 ... Deficiency • Drugs
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
Vitamin B12 (Cobalamin ... • Common Causes ... dietary intake (e.g ... : • Worsening macrocytic ... , can consider IM
#ICUCard RENAL GFR 90-131 mL/min ((140-age)*Wt)/(72*Cr) Glomerular Filtration Rate (Cockcroft) CI Cr 90-131 mL/min (CrU * volume)/CrS Creatinine Clearance FENa 0.0-1.0 % ((U/P Na)/(U/P Cr))*100 Fractional Excretion of Na+ Na req mEq (125-Na)*0.6*Wt Required Sodium FE Urea
assessment required DRUGS ... Bumetanide: IV or IM ... over 12-24hours ... x4 q15-30min) *IM ... *Check drug packet
Subacute Thyroiditis Also known as: de Quervain’s thyroiditis, granulomatous thyroiditis, or viral thyroiditis What? Postviral inflammatory process caused by
inflammatory process caused ... Cytomegalovirus (CMV ... • Parvovirus B19 ... • Aspirin (e.g., ... anti-inflammatory drugs
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