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Algorithm for the Evaluation of Anemia #Diagnosis #EM #IM #Honc #Anemia #Differential #Workup #Algorithm #Microcytic #Macrocytic
Evaluation of Anemia ... #Diagnosis #EM ... #IM #Honc #Anemia ... Workup #Algorithm #Microcytic ... #Ddxof
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Framework by MCV Microcytic ... Infections Macrocytic ... , B12 deficiency ... Orotic aciduria, Drugs ... (e.g., hydroxyurea
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
RBC) Morphology Microcytic ... (sometimes) Macrocytic ... Chemotherapy (e.g ... disorders, Oxidative drugs ... Diseases #Red #BloodCell
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Blood Smear • Drugs ... • Dietary Deficiency ... Increased Requirement (e.g ... B12 and Folate Deficiency ... Liver Disease #Macrocytic
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
B12 (Cobalamin) Deficiency ... : • Worsening macrocytic ... anemia, yellow ... , can consider IM ... B12 #Cobalamin #Deficiency