197 results
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic Syndrome ... nephrotic/nephritic syndromes ... dysmorphic RBCs in urine ... Nephritic #Nephrotic #Syndrome ... Algorithm #Nephrology #Diagnosis
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
and Nephrotic Syndromes ... Nephritic syndrome—due ... RBC casts in urine ... Nephritic #Nephrotic #Syndromes ... Proteinuria #Nephrology #Diagnosis
Purple Urine Bag Syndrome
Chronic, indwelling catheter + bacteriuria (Providencia, Klebsiella, E.coli*) + alkaline urine
Tryptophan → Indoxyl
Purple Urine Bag ... Syndrome Chronic ... #Bag #Syndrome ... #PUBS #pathophysiology ... #differential #diagnosis
Metabolic Pathways of Purple Urine Bag Syndrome: Adopted from chart originally published in Purple Urine Bag
Pathways of Purple Urine ... Bag Syndrome: Adopted ... Bag Syndrome: A ... #Pathophysiology ... #Bag #Syndrome
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
- Differential Diagnosis ... disease - Alport syndrome ... pain hematuria syndrome ... - RBC casts → Diagnostic ... • Nutcracker syndrome
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
Pathophysiology ... of Tumor Lysis Syndrome ... Nephropathy (low urine ... nephropathy (high urine ... #TumorLysis #Syndrome
Urine Microscopy Crystals
Uric Acid crystals:
 - Formation promoted by acidic urine
 - Seen in tumor lysis
Urine Microscopy ... promoted by acidic urine ... in tumor lysis syndrome ... - Diagnostic of ... #Microscopy #Crystals
Parkinson's Plus Syndromes - Atypical Parkinsonism
Main motor symptoms:
 • Tremors
 • Limb rigidity
 • Bradykinesia
Other symptoms
Parkinson's Plus Syndromes ... Parkinson's plus syndrome ... • Corticobasal syndrome ... Parkinsons #Plus #Syndromes ... #Parkinsonism #diagnosis
Evaluation of Secondary Hypertension
 • Primary aldosteronism - PRA, PAC
 • Renal artery stenosis - Renal
fT4 • Cushing syndrome ... cortisol. 24-h urine ... Mineralocorticoid excess syndromes ... Evaluation #workup #diagnosis
Algorithm for Differentiating Gitelman syndrome from Bartter syndrome
 • Urine Chloride
 • Urine Ca/Cr ratio

Dr. Krithika
Differentiating Gitelman syndrome ... from Bartter syndrome ... • Urine Ca/Cr ... #Gitelman #syndrome ... #hypokalemia #diagnosis