23 results
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
CNS Infection in ... HIV / AIDS - Differential ... CNS Opportunistic ... #differential # ... diagnosis #AIDS
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
infects the CNS ... mononuclear cells in the CNS ... Diagnosis: MRI ... The clinical syndrome ... #AIDS #Neurology
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
1) Clinical diagnosis ... hydrocephalus, HIV ... MRI, iADL scale, ... Aphaso-apraxo-agnosia syndrome ... #Differential #
Localizing Extraocular Movement Disorders
 • CN Ill (Oculomotor) Nerve Palsy 
 • CN IV (Trochlear) Nerve
IV (Trochlear) ... Syndrome • Cavernous ... Sinus (CS) Pathology ... ophthalmology #neurology #differential ... #diagnosis #ocular
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Scleromyxedema (CNS ... +GI+CVS+joints) ... • Amyloidosis (CVS ... Hematology #Monoclonal #Differential ... #Diagnosis #Oncology
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
Heat Stroke - Differential ... Diagnosis Framework ... No significant CNS ... CNS dysfunction ... temp > 104 F - CNS
Approach to Headaches - Differential Diagnosis Algorithm

Red flags (PHANTOMS):
 • Pattern change, progressively worse, papilledema
 •
Diagnosis Algorithm ... papilledema • Horner syndrome ... history of cancer, HIV ... Systemic symptoms and ... brain lesion • CNS
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
nervous system (CNS ... important, as early diagnosis ... pachymeningitis • HIV ... noninflammatory #differential ... #diagnosis
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Weakness - Differential ... Diagnosis Framework ... pulmonary etc) • CNS ... parainfluenza, Coxsackie, HIV ... #Diagnosis #neurology
Approach to the A-a Gradient
A-a gradient = PAO2 - PaO2
A-a gradient = [FiO2 x (Patm -
Hypoventilation: CNS ... Hypoventilation Syndrome ... : Atelectasis, ARDS ... Hypoxia #hypoxemia #differential ... #diagnosis