818 results
Systemic Lupus Erythematosus (SLE): Pathogenesis

 • Genetic factors (Mutations in HLA- DR2/HLA-DR3 genes, complement genes, cytokine
Systemic Lupus Erythematosus ... retroviruses), Drugs (minocycline ... Multiple immune system ... IL-6, IL-10 #Systemic
Drug Induced Systemic Lupus Erythematosus
> 100 drugs have been associated with drug-induced SLE
High risk (>5%):
 •
Drug Induced Systemic ... Chlorpromazine, Isoniazid, Minocycline ... DrugInduced #SLE #Systemic
Pyoderma Gangrenosum (PG)
50 M Crohn’s dz had a small pustule on the ankle 4 mo ago
association w/ systemic ... components of immune system ... topical therapy, & systemic ... 0.1% ointment or systemic ... azathioprine, minocycline
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
PTU (50%) and minocycline ... months to years) Systemic
Antibiotics with MRSA Coverage

Oral: Doxycycline, Minocycline, Clindamycin, TMP-SMX
IV: Vancomycin, Daptomycin, Telavancin, Ceftaroline, Dalbavancin, Oritavancin, Tigecycline
Oral and
: Doxycycline, Minocycline
The parasympathetic and sympathetic systems - Activation and inhibition pathways by organ system

#Sympathetic #Parasympathetic #Systems #Pathways
and sympathetic systems ... pathways by organ system ... Parasympathetic #Systems
Commonly Used Clinical Grading Systems
 • Edema Grading Scale
 • Hepatic Encephalopathy Grading (West Haven Criteria)
Clinical Grading Systems ... Criteria) • Systolic ... DharSaty #Grading #Systems
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Systemic Sclerosis ... Scleroderma) Multi-system ... Limited cutaneous systemic ... knees • Diffuse systemic ... and/or trunk • Systemic
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
• Homogeneous: Systemic ... ) • Speckled: Systemic ... Nucleolar: Diffuse systemic ... Centromere: Limited systemic ... • Peripheral: Systemic
A good approach when dealing with hypotension at the bedside includes using the following systematic four
the following systematic ... Systemic Vascular