9 results
Management of Anthracyclines and HER2 Antagonist Cardiotoxicity
Anthracyclines cause cardiomyopathy:
 ✖ Reduction in left ventricular ejection fraction
HER2 Antagonist Cardiotoxicity ... Identify and treat modifiable ... Identify and treat modifiable ... Anthracycline #HER2 #Cardiotoxicity
Risk factors for atherosclerosis

Modifiable risk factors:
 - Dyslipidemia (elevated LDL, decreased HDL)
 - Tobacco smoking
 -
atherosclerosis Modifiable ... activity Non-modifiable
Chemotherapy Toxicity Bear Mnemonic - Cumulatively Toxic Drugs and their Rescues
 • Asparagine: neurotoxicity
 • Cisplatin:
Dexrozoxane (for cardiotoxicity
Gonorrhea: Pathophysiology

 - Neonatal Transmission -> Direct contact of patient mucosa with mother's infected mucosa while
bacterial reduction modifiable
Diverticulitis - Modifiable Risk Factors
Diet: Fibre, Nuts, Popcorn, Vegetarian diet, Western dietary pattern, Red meat
Lifestyle: Physical
Diverticulitis - Modifiable ... Diverticulitis #Diet #Modifiable
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
patient have any modifiable
Management of Immune Checkpoint Inhibitor (ICI) Induced Cardiotoxicity
Problem - Immune checkpoint inhibitors (ICIs) are associated with
(ICI) Induced Cardiotoxicity ... associated with cardiotoxicity ... ✖ Cardiotoxicity ... ICI-associated cardiotoxicity ... Inhibitor #ICI #Cardiotoxicity
Loperamide and QT Prolongation - Recently, there have been increasing cases of cardiotoxicity associated with high-dose
increasing cases of cardiotoxicity ... the mechanism of cardiotoxicity
Vaccines - Impact Timeline
Diphtheria
Polio
Pertussis
Hepatitis B
Measles
Chickenpox
Hepatitis A
Mumps
Rubella

Bubbles represent reported U.S. cases, but not all diseases were notifiable
diseases were notifiable