14 results
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm
 • Reactive (Inflammatory / Infectious)
 •
Causes of Diffuse ... and Localized Lymphadenopathy ... - Differential ... Algorithm #Causes #Hematology ... #Oncology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Volume (MCV) - Differential ... B12 - Anti-IF Antibodies ... B12 - Anti-IF Antibodies ... • Rule out B12 and ... Algorithm #Causes #Hematology
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... • Nucleolar: Diffuse ... #Antinuclear #Antibodies ... #rheumatology #diagnosis ... #differential
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Antibody refers to antibodies ... • Nucleolar: Diffuse ... #rheumatology #diagnosis ... #differential
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Petechial Rash - Differential ... Thrombocytopenia - Abnormal ... deficiency - Abnormal ... for hepatitis B and ... of antinuclear antibodies
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
Idiopathic • Normal ... Purpura Anti-GBM antibodies ... (C-ANCA): GPA > ... Glomerulonephritis #Vasculitis #differential ... diagnosis #algorithm #rheumatology
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
Elevated ESR, Normal ... muscle weakness • Normal ... Lupus Myopathy • Diffuse ... Myopathies #myopathy #differential ... diagnosis #comparison #rheumatology
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... antiphospholipid antibodies ... amyloidosis #Abnormal ... Causes #diagnosis #differential ... #hematology #coagulation
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... antiphospholipid antibodies ... antiphospholipid antibodies ... Causes #diagnosis #differential ... #hematology #coagulation
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Malignancy (e.g. hematologic ... pneumonitis • Diffuse ... diffuse peritonitis ... 1, SCL-70, RNP antibodies