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causes abnormal aptt hepatology interpretation prolonged albumin bleeding bruising chemistry dic disseminated fluid gradient hemostasis intravascular lfts management rvalue saag
Deciphering the SAAG - Serum to Ascites Albumin Gradient Ascites is either made in the liver sinusoid
or not by the liver ... Matherly @liverprof #Diagnosis ... #Hepatology #SAAG ... Interpretation #Differential ... #Analysis
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Prolonged PT ... Fibrinogen: ↓ • PT ... DIC • Severe Liver ... #diagnosis #causes ... treatment #management #hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Early liver disease ... Reduced liver synthesis ... Prolonged #Causes #diagnosis ... #differential # ... hematology #coagulation
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... thrombin inhibitors, heparin ... • Reduced liver ... #differential # ... hematology #coagulation
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
• Albumin • Coagulation ... factors: PT/INR ... replaced by non-hepatic ... #chemistry #diagnosis ... #differential #
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
of Hemostasis - Differential ... Diagnosis Framework ... inhibitor of a coagulation ... Acquired: • Heparin ... #Diagnosis #Hematology
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