6 results
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Prolonged PT ... Fibrinogen: ↓ • PT ... DIC • Severe Liver ... #diagnosis #causes ... treatment #management #hematology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Early liver disease ... Reduced liver synthesis ... Prolonged #Causes #diagnosis ... #differential #hematology ... #coagulation
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... thrombin inhibitors, heparin ... • Reduced liver ... #differential #hematology ... #coagulation
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
• Albumin • Coagulation ... factors: PT/INR ... replaced by non-hepatic ... disease: > 2 • NASH ... #chemistry #diagnosis
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
- Differential Diagnosis ... inhibitor of a coagulation ... Acquired: • Heparin ... #Differential #Diagnosis ... #Hematology
Monkeypox Skin Rash
30 yr F and her 6 yr daughter purchased 2 prairie dogs 10 days
Monkeypox Skin Rash ... dogs 10 days ago (pers ... Now pt & daughter ... Diagnosis? ... clinical #photo #dermatology