11 results
Ulcerative Blastomycosis Skin Lesion
57 asymptomatic M from Indiana nonpruritic, painless, progressive skin lesion lower back x
an old house & works ... Diagnosis? ... University Infectious Diseases ... Blastomycosis #SkinRash ... #dermatology #clinical
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Signs and Symptoms ... Examination: • Skin ... but elevated as disease ... Diagnosis: • ... #workup #hepatology
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Multi-system autoimmune disease ... thickening Signs ... pericarditis • Hepatic: PBC ... #diagnosis #signs ... symptoms #testing #workup
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
more): Genital ulceration ... response to local skin ... , ulcerative colitis ... #signs #symptoms ... #rheumatology #
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... Episcleritis Signs ... , breast CA - Hematologic ... - CBC may also ... #diagnosis #dermatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... Alpha & Mu) Skin ... +Organomegaly+↑RBC ... Paraproteinemias #Hematology ... #Differential #Diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... Hepatomegaly • Skin ... cells can indicate disease ... #workup #oncology ... #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... • Cogan Syndrome ... purpura: strong sign ... Lab Tests: • CBC ... #rheumatology #
Monkeypox Skin Rash
30 yr F and her 6 yr daughter purchased 2 prairie dogs 10 days
Monkeypox Skin Rash ... dogs 10 days ago (pers ... Diagnosis? ... University Infectious Diseases ... #SkinRash #clinical
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... gammopathy, and skin ... changes (POEMS syndrome ... autoimmune hepatitis, PBC ... #differential #diagnosis