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differential management dermatology blood classification hemolytic product vasculitis antinxp2 antinxp2dm aplastic clinical dermatomyositis erythematosus extravascular hemolysis intravascular leukemia lupus mds
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... Other agents ex. lead ... • Transfusion reactions ... #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... disease, Copper and lead ... Extravascular #Causes ... #hematology #anemia
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... purple, hemorrhagic skin ... - Hemolytic anemia ... fever • Drug reactions ... #hematology #rheumatology
Monkeypox What? Monkeypox virus belongs to the family Poxviridae, subfamily Chordopoxvirinae, and genus orthopoxvirus Viral zoonotic disease that is
disease that is caused ... Characteristic Rash ... Umbilification - Rash ... Polymerase chain reaction ... #MPOX #Diagnosis
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
maculopapular rash ... Causes purpura & ... infections with skin ... #Transfusion #diagnosis ... #management #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... Headaches • Pale skin ... and petechiae Causes ... #oncology #hematology ... #diagnosis #management
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
maculopapular rash ... Causes purpura & ... infections with skin ... #Transfusions #diagnosis ... #management #hematology
Monkeypox Skin Rash 30 yr F and her 6 yr daughter purchased 2 prairie dogs 10 days
Monkeypox Skin Rash ... dogs 10 days ago (pers ... Diagnosis? ... .’ 1st human case ... clinical #photo #dermatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Differential Diagnosis ... Non-autoimmune rheumatologic ... lymphopenia, low PLT • Anemia ... #Rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Alpha & Mu) Skin ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Differential #Diagnosis ... #Oncology
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