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differential oncology dermatology bleeding management rheumatology algorithm alopecia anemia aplastic bruising chronic clinical cll cryofibrinogenemia eosinophil eosinophilia gap globulin hair
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... Chronic inflammatory disorders ... Myelodysplastic syndrome ... Chronic myeloid leukemia ... #Causes #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... purple, hemorrhagic skin ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... #hematology #rheumatology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... organ-specific signs ... symptoms (eg, skin ... #Differential #diagnosis ... #hematology #eosinophilia
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... Hepatomegaly • Skin ... lymphoproliferative disorders ... #diagnosis #workup ... #oncology #hematology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Rare Disorder: ... Episcleritis Signs ... Causes: - Idiopathic ... cutis Diagnosis ... #diagnosis #dermatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... • Tumor lysis syndrome ... CLL -> Invade Skin ... #Hematology #Oncology ... #Diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... just beneath the skin ... Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... #diagnosis #hematology
Allopecia - Differential Diagnosis Framework for Hair Loss Localized / Focal Hair Loss Pattern: • Scarring Alopecia:
- Differential Diagnosis ... Capitis - Skin ... , Loose anagen syndrome ... Examination: • Signs ... Examine the entire skin
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Headaches • Pale skin ... and petechiae Causes ... virus (EBV) • Leukemia ... Anemia #oncology #hematology ... #diagnosis #management
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
cryoglobulinemia Associated Disorders ... Cryofibrinogenemia Diagnosis ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... hematology
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