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differential disorders leukemia algorithm anemia aplastic arterial bleeding chronic cll dermatology embolism eosinophil eosinophilia history lymphocytic management mds monoclonal myelodysplasia
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... purple, hemorrhagic skin ... vascular disorders, coagulation ... #Differential #Diagnosis ... #hematology #rheumatology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
organ-specific signs ... symptoms (eg, skin ... #Differential #diagnosis ... #hematology #eosinophilia
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
- Differential Diagnosis ... Testosterone - Coumadin skin ... intravascular coagulation ... pathophysiology #hematology ... #differential #diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... Hepatomegaly • Skin ... phenomenon CLL Diagnosis ... #workup #oncology ... #hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Alpha & Mu) Skin ... thrombosis+Pulm HTN+skin ... Paraproteinemias #Hematology ... #Differential #Diagnosis ... #Oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Headaches • Pale skin ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
CLL -> Invade Skin ... #Leukemia #Hematology ... #Oncology #Diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Helpful Clinical Features in Evaluating Bleeding Disorders Age of onset • Neonate - in 20% of haemophilias,
membrane bleeding and skin ... Disorders #History #peds ... #pediatrics #diagnosis ... #hematology #primarycare
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