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rheumatology cryoglobulinemia differential acute aki behcet cryoglobulinemic cryoglobulins disease erythematosus injury involvement kidney lupus monoclonal oncology paraproteinemias renal signs sjogrens
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
Kidney Injury - Classification ... a.k.a. cardiorenal syndrome ... - Small vessel vasculitis ... causes: sepsis, meds ... #diagnosis #nephrology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... : • Behçet Syndrome ... • Cogan Syndrome ... #rheumatology # ... classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Purpura - Skin ... reticularis & skin ... Labs/Diagnosis: ... #types #classification ... #rheumatology #
Renal involvement in 35% of mixed cryoglobulinemia vasculitis Associated with : • Absence of skin
cryoglobulinemia vasculitis ... • Absence of skin ... min/1.73 m2 at diagnosis ... #Management #Rheumatology ... Cryoglobulinemic #Nephrology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
, small-vessel vasculitis ... response to local skin ... test (this is a skin ... #diagnosis #management ... signs #symptoms #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Alpha & Mu) Skin ... thrombosis+Pulm HTN+skin ... Autoimmunity: • -MM/WM: Vasculitis ... Paraproteinemias #Hematology ... #Differential #Diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Disease Classification ... Differential Diagnosis ... Malignancy (e.g. hematologic ... Seizures • Strokes Skin
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Diagnosis: • Dry ... ) • Cutaneous vasculitis ... Nephrogenic DI Hematologic ... : 2% Systemic Vasculitis ... Diagnosis #Management
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