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Red cell autoagglutination is the process whereby red cells clump together forming aggregates. This is seen
or Infectious mononucleosis ... individual’s red blood ... Clinical #Path #Blood
Red cell autoagglutination is the process whereby red cells clump together forming aggregates. This is seen
or Infectious mononucleosis ... individual’s red blood ... Clinical #Path #Blood
Infectious Mononucleosis - Diagnosis and Serologies
Triad of fever, tonsillar pharyngitis, and lymphadenopathy
Heterophile is not recomended by
Infectious Mononucleosis ... #Infectious #Mononucleosis
CMV vs EBV - Mononucleosis
Acute CMV Infection:
 • Asymptomatic (most common)
 • Infectious mononucleosis (fever/chills, malaise)
CMV vs EBV - Mononucleosis ... • Infectious mononucleosis ... #CMV #EBV #Mononucleosis
Differential Diagnosis of Fever and Splenomegaly
 - Typhoid
 - Infective endocarditis
 - Miliary tuberculosis
 - Hodgkin
Hodgkin lymphoma - Mononucleosis
Clinical Manifestations of Human Herpes Viruses (HHV)

Herpes simplex virus 1	HSV-1	Frequently subclinical (80-90%) Oral lesions (10-20%) congenital
Cytomegalovirus CMV Mononucleosis-like ... Epstein—Barr virus EBV Mononucleosis
Microbial Etiology of Acute Pharyngitis - IDSA
Bacterial
 • Group A streptococcus - Pharyngotonsillitis, scarlet fever
 •
EBV - Infectious mononucleosis ... Cytomegalovirus - CMV mononucleosis
Black and Bloody Stools - Melena and Hematochezia
Melena - Refers to passage of black, tarry (sticky
Black and Bloody ... Occult blood tests ... least 60 mL of blood ... transit is slow, blood ... Red Blood in the
The test characteristics of the heterophile antibody (AKA the monospot test) are not perfect and can
#Diagnosis #Mononucleosis
Causes of Pediatric Stridor - Differential Diagnosis Algorithm
Present Since Infancy with No Respiratory Distress:
 • Laryngomalacia
Present
Epiglottitis* • Mononucleosis