11 results
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
Myositis and Myopathies ... Anti-Jo, +Anti-Mi2 Dermatomyositis ... muscle weakness, rash ... Inclusion Body Myositis ... Myopathies #myopathy #differential
Causes of Rhabdomyolysis - Differential Diagnosis
 • Drugs & Toxins (Statins, alcohol, cocaine)
 • Direct Muscle
Causes of Rhabdomyolysis ... - Differential ... Damage (Trauma/crush ... Muscle Disease (myositis ... #Diagnosis #Causes
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... Tetanus, Transverse Myelitis ... , Polymyositis/dermatomyositis ... Neuromuscular #Weakness #Causes ... #differential #
Creatine Kinase - Causes of Elevated CK Levels
Acute CK Elevation (Pain > Weakness):
 • RHABDOMYOLYSIS
Creatine Kinase - Causes ... Subacute to Chronic Causes ... Inflammatory myopathy: dermatomyositis ... Inclusion body myositis ... #Elevated #CK #differential
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
Leg Pain - Differential ... Compartment syndrome • Myositis ... • Trauma • Crush ... blunt trauma, crush ... #Leg #pain #differential
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Rhabdomyolysis - Differential ... Immobilization, Crush ... (polymyositis/Dermatomyositis ... Rhabdomyolysis #Differential ... Management #Summary #causes
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... Management Summary Causes ... Immobilization - Crush ... : Polymyositis/Dermatomyositis ... Rhabdomyolysis #Differential
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
evidence of (fatigue, rash ... Photosensitive rash ... permanent alopecia Differential ... Still disease, dermatomyositis ... • Transverse Myelitis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitides - Differential ... tract, and often causes ... Conjunctivitis, mucositis ... - Rash, arthritis ... ear disease Differential
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis ... - Differential ... Symptoms: • Gottron rash ... statins - probably caused ... #rheumatology #differential