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diagnosis rheumatology management systemic activation antimda5 antimda5dm antinxp2 antinxp2dm comparison differential druginduced hematology joint macrophage mas pain rashes skin summary
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
• SLE • Human ... Vesicopustule on erythematous ... lesions • Discoid lupus ... erythematosus ... #dermatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... Positive in 60-80% of cases ... #Erythematosus
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Suspect: Clinical ... rash • Erythematous ... Still disease, dermatomyositis ... lymphoproliferative syndrome Clinical
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... NPSLE rare, Malar rash ... Discontinuation of causal ... Erythematosus ( ... 40, F:M 9:1 • Clinical
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
with edema • Erythematous ... rash on the face ... violaceous macules and erythematous ... auricular papules Clinical ... #rheumatology #dermatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Systemic lupus ... erythematosus ... SJIA], systemic lupus ... erythematosus [ ... SLE], AOSD) • Infection
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
with edema • Erythematous ... violaceous macules and erythematous ... auricular papules Clinical ... Muscle atrophy may cause ... #rheumatology #dermatology
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