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microscopy clinical casts diagnosis nephrology urine auer hematology muddybrown rods smear apl auerrods blood bloodsmear differential path pathology acute aml
Examples of varying granular and granular/waxy mixed casts: A: coarse granular/broad-waxy (and surrounding white blood cells);
Examples of varying granular ... and granular/waxy ... /muddy brown granular ... , C and D: muddy ... brown granular/
Muddy Brown Granular Casts three ways - Brightfield, Darkfield, Phase Contrast. Dr. Vipin Varghese @vipvargh #Muddy #Brown #Granular
Muddy Brown Granular ... Varghese @vipvargh #Muddy ... #Brown #Granular
Granular & “Muddy Brown” Casts on Urine Microscopy A. Finely granular cast B. slightly coarser granular cast
Granular & “Muddy ... Finely granular ... slightly coarser granular ... coarse (c) and muddy ... brown (mb) granular
Urinary Casts and Disease Associations Hyaline - May be nonspecific; seen in normal individuals or during severe
concentrated urine Granular ... cellular casts "Muddy-brown ... " heme-granular
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
promyelocytic leukemia ... overt cytoplasmic granules ... promyelocytic #leukemia
T-LGL leukemia - T-CeIl Large Granular Lymphocytic Leukemia Clinical - Persistent (>6mo) lymphocytosis (2-20k) with proven clonality
T-LGL leukemia - ... T-CeIl Large Granular ... Lymphocytic Leukemia ... Predominantly leukemic ... #Lymphocytic #Leukemia
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview ... , CLL Acute leukemias ... Chronic leukemia ... Lymphoblastic Leukemia ... distinctive primary granules
Here are very large, immature myeloblasts with many nucleoli. A distincitve feature of these blasts is
of crystallized granules ... acute myelogenous leukemia
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
abundant cytoplasmic granules ... promyelocytic leukemia ... decreased secondary granules ... acute myeloid leukemia ... mixed lineage leukemia
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 Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
histamine in their granules ... Chronic myeloid leukemia ... Acute myeloid leukemia ... Acute basophilic leukemia
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