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clinical microscopy casts nephrology urine diagnosis pathology smear apl auerrods path rods actinomycosis blood bloodsmear derm hematology leukemia muddybrown actinomyces
Examples of varying granular and granular/waxy mixed casts: A: coarse granular/broad-waxy (and surrounding white blood cells);
Examples of varying granular ... and granular/waxy ... /muddy brown granular ... , C and D: muddy ... brown granular/
Muddy Brown Granular Casts three ways - Brightfield, Darkfield, Phase Contrast. Dr. Vipin Varghese @vipvargh #Muddy #Brown #Granular
Muddy Brown Granular ... Varghese @vipvargh #Muddy ... #Brown #Granular
Granular & “Muddy Brown” Casts on Urine Microscopy A. Finely granular cast B. slightly coarser granular cast
Granular & “Muddy ... Finely granular ... slightly coarser granular ... coarse (c) and muddy ... brown (mb) granular
Auer Rods - Bone marrow aspiration revealed 5% blasts and 65% promyelocytes; many promyelocytes had prominent
Auer Rods - Bone ... had prominent Auer ... APL #AuerRods #Auer ... Smear #Microscopy #NEJM
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
overt cytoplasmic granules ... , and Auer rods. ... KyleBradleyMD #Auer
Here are very large, immature myeloblasts with many nucleoli. A distincitve feature of these blasts is
a linear red "Auer ... of crystallized granules ... Smear #Microscopy #Auer
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
abundant cytoplasmic granules ... with occasional Auer ... decreased secondary granules ... consistent with Auer ... addition to APL, Auer
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 Urinary Casts and Disease Associations Hyaline - May be nonspecific; seen in normal individuals or during severe
concentrated urine Granular ... cellular casts "Muddy-brown ... " heme-granular
Urine Microscopy - Casts Acellular Casts • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
• "Muddy Brown ... ) • Granular Casts
Atlas of Urine Microscopy Findings • Epithelial cells - Normal • Renal tubular cells - Acute
renal disease • Granular ... renal disease • “Muddy
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